Infigratinib靶向的FGFR3(成纤维细胞生长因子受体3)正是驱动ACH疾病发生的关键靶点,2月12日,BridgeBio公布Infigratinib在ACH中取得的首个具有统计学显著改善意义的3期顶线结果,公司计划下半年向FDA提交新药申请。
"Your heart is having an easy time, your muscles and bones are having an easy time. You're floating around the space station in this wonderful zero gravity environment.
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However, the incident did force NASA to cancel a spacewalk planned for January 8. Soon after that, the agency announced it would be ending the Crew-11 mission a month early. The four-person crew included Fincke, NASA astronaut Zena Cardman, Japanese astronaut Kimiya Yui and Russian cosmonaut Oleg Platonov.
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